ClinicShort Communication | DOI: https://doi.org/10.31579/2834-5010/014
Malt lymphoma of the ovary!
- Hilary Denis Solomons *
P.O.Box 64203, Highlands North, 2037. South Africa.
*Corresponding Author: H.D.Solomons, P.O.Box 64203, Highlands North, 2037. South Africa.
Citation: Hilary Denis Solomons., (2024). Malt lymphoma of the ovary!. International Journal of Clinical Therapeutics. 3(2); DOI: 10.31579/2834-5010/014
Copyright: © 2024, Hilary Denis Solomons. Nguyen., this is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 01 February 2024 | Accepted: 20 February 2024 | Published: 20 March 2024
Keywords: thyroid; chemotherapy; laporoscopy; chronic
Abstract
At the same time one looks for Helicobacter pylori.The disease may be associated with autoimmune disorders such as Sjorgren’s syndrome or Hashimoto’s thyroiditis.
Introduction
Malt lymphoma of the ovary is rare but does occur. Also known as maltoma involves the mucosa associated lymphoid tissue . Usually the ovary or stomach is involved but any mucousal site can be affected.
The B cells in the marginal zone are involved resulting in a extranodal marginal zone B cell lymphoma.
Helicobacter pylori is associated with MALT lymphoma ( chronic inflammation !)
The initial diagnosis is made on biopsy by means of laporoscopy or eosophagogastroduodenoscopy. At the same time one looks for Helicobacter pylori.
The disease may be associated with autoimmune disorders such as Sjorgren’s syndrome or Hashimoto’s thyroiditis.
Thus the ovary , salivary gland or thyroid may be involved.
If limited to the stomach the disorder may respond just to antibiotics.
However surgery or chemotherapy may be necessary.
A t(11;1809q21;q21 ) chromosomal translocation ,giving rise to a AP12-MLT fusion gene , is predictive of a poor response to eradication therapy.
However the locus 14q32 may also be involved!
