Short Communication | DOI: https://doi.org/10.31579/2835-9232/076
Epidemiological information from general medicine. The concept of minimum morbidity rates
- Jose Luis Turabian *
*Corresponding Author: Jose Luis Turabian, Specialist in Family and Community Medicine Health Center Santa Maria de Benquerencia. Regional Health Service of Castilla la Mancha (SESCAM), Toledo, Spain.
Citation: Jose L. Turabian, (2024), Epidemiological information from general medicine. The concept of minimum morbidity rates, International Journal of Clinical Epidemiology, 3(5); DOI:10.31579/2835-9232/076
Copyright: © 2024, Jose Luis Turabian. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 19 September 2024 | Accepted: 29 September 2024 | Published: 17 October 2024
Keywords: epidemiology; health information; population; representative; survey; general practice
Abstract
Health surveys are commonly used to measure morbidity, but these types of instruments are not free from errors and difficulties. Although the cost of cross-sectional studies is relatively lower than that of other epidemiological designs, such as cohort studies, this cost is not negligible, as they require some fieldwork, use questionnaires that are applied by interviewers, or need to take biological samples, or anthropometric measurements, and medical examinations, with specific technical equipen.
In health surveys, certain “levels” or “filters” have been considered. Level 1 or the first filter represents the total morbidity detectable in the community, determined by screening (questionnaires, tests, etc.).
Introduction:
Health surveys are commonly used to measure morbidity, but these types of instruments are not free from errors and difficulties [1-3]. Although the cost of cross-sectional studies is relatively lower than that of other epidemiological designs, such as cohort studies, this cost is not negligible, as they require some fieldwork, use questionnaires that are applied by interviewers, or need to take biological samples, or anthropometric measurements, and medical examinations, with specific technical equipment [4].
In health surveys, certain “levels” or “filters” have been considered [5]. Level 1 or the first filter represents the total morbidity detectable in the community, determined by screening (questionnaires, tests, etc.). Carrying out a screening in the population (for example with questionnaires...) could find not only those patients who do not go to the general practitioner (GP), but also those who go to the GP but are not recognized as sick.
After passing this level 1, the patient becomes an element that expresses morbidity in primary care (level 2). Only a proportion of patients who reach to GP will be diagnosed as cases compared to those found by screening in the community. The spontaneous consultation of the patient with the GP depends on what the person understands by disease or the subjective assessment of his symptoms, and on the concept of disease by the doctor, in addition to the accessibility to the doctor, both in terms of time and economic cost.
Thus, morbidity data at the level of the GP consultation can be considered as “prevalence or minimum incidence.” In certain environments, the incidence rates of a health problem are difficult to obtain for different reasons, both in determining the numerator (such as when clinical information is missing, lack of infrastructure, laboratory capacity, etc.), and in determining the denominator (for example, complex urban environment where hospitals act as a primary care level). To fill this gap, in these cases, we speak of estimation of the “minimum” incidence [6]. That is, the term “minimum incidence/prevalence rates” is used when the estimates do not necessarily cover the entire population. The concept of “minimum incidence/prevalence” is useful in epidemiology and it has been used with some frequency in different studies [7-16].
Registries in general practice are key sources for morbidity estimates, especially if all people are registered in a general practice and if GP is the gatekeeper of health care; So, diagnoses from medical specialists and other health care providers will also be known by the GP [17, 18]. Of the patients diagnosed as a case by the GP at the general medicine level, a small proportion will go to level 3: the cases diagnosed at the specialized level, both at the out-of-hospital or hospital level (level 4).
It must also be taken into account that prevalence of a disease is the proportion, in a certain population, of cases number at a point in time. Prevalence is an appropriate measure only in such relatively stable conditions, and it is unsuitable for acute disorders. Even in a chronic disease, the manifestations are often intermittent. In consequence, a “point" prevalence, based on a single examination, at one point in time, tends to underestimate the condition's total frequency. If repeated or continuous assessments of the same individuals are possible, a better measure is the period prevalence defined as the proportion of a population that is cases at any time within a stated period. It is necessary to take into account that in general medicine, continuity of care gives rise to repeated or continuous assessments, so the results of prevalence studies may be more accurate, and so avoid the possible underestimation of cross-sectional studies.
So, collection of data in general medicine is cumulative and continuous; the path of all patients begins and ends with the GP (17). Hay que recordar que in UK, 66 percent of respondents consult with a physician at least once a year. Furthermore, 24 percent of those will see their doctor three times or more in a year. And, in countries such as France and Spain there is a higher share of people consulting a physician at least once a year [19].
General practice is an important source of information on the occurrence and distribution of diseases in the population [20]. Certainty of a diagnosis is not only important for the patient, but also for morbidity studies. Diagnoses of diseases recorded in general practice are generally valid with low numbers of false positive cases [21]. Concordance between health survey and general medicine prevalence data are good for chronic conditions [20, 22-25].
Epidemiology places clinical problems in the community perspective, their size and distribution, reveals problems and indicates which population should be studied, and how much action and where it is needed [26, 27]. The GP is in a rare position that combines the individual and community dimensions, and there is a great need to extend the clinical horizons to the epidemiological and community aspects of primary care. Unless GPs can follow the health and disease patterns of the community in which their patients live, they will not be able to know if the individual care they provide is relevant or effective. Individual and community care are not alternatives to the care given by GP. What is traditionally called individual, family and community attention are elements of the same reality and cannot be separated: that is, there is no individual attention, but always is both familial and community (17) In this way, the importance of research and Epidemiology at the GP level is often overlooked. There have been GPs pioneers who studied the problems of their patients with scientific rigor. Some of them have been recognized for their seminal work in the last century [28-29]. In this context, a useful alternative to obtain epidemiological information on morbidity is the use of data generated in the GP's office, by identifying of cases at patient presentation at the clinic. These data represent the “minimum morbidity” of the community.
References
- Margozzini P, Tolonen H, Bernabe-Ortiz A et al. (2023) National Health Examination Surveys: an essential piece of the health planning puzzle.
View at Publisher | View at Google Scholar - Whiffen T, Akbari A, Paget T, Lowe S, Lyons R (2020) How effective are population health surveys for estimating prevalence of chronic conditions compared to anonymised clinical data? Int J Popul Data Sci; 5(1): 1151.
View at Publisher | View at Google Scholar - Nygaard SS, Srivarathan A, Mathisen J, et al. (2022) Challenges and lessons learnt from conducting a health survey in an ethnically diverse population. Scand J Public Health; 50(7): 995-1006.
View at Publisher | View at Google Scholar - Hernández B, Velasco-Mondragón HE (2000) [Cross-sectional surveys]. Salud pública Méx; 42(5).
View at Publisher | View at Google Scholar - Marcus AC, Murray Parkes C, Tomson P, Johnston M (1991) Psychological problems in general practice. Oxford: Oxford University Press.
View at Publisher | View at Google Scholar - Bar-Zeev N, Mtunthama N, Gordon SB, Mwafulirwa G, French N (2015) Minimum incidence of adult invasive pneumococcal disease in Blantyre, Malawi an urban african setting: a hospital based prospective cohort study. PLoS One; 3;10(6): 0128738.
View at Publisher | View at Google Scholar - Abo YN, Oliver J, McMinn A (2023) Increase in invasive group A streptococcal disease among Australian children coinciding with northern hemisphere surges. Lancet Reg Health-West Pac.
View at Publisher | View at Google Scholar - Narayan SK, Gorman G, Kalaria RN, Ford GA, Chinnery PF (2012) The minimum prevalence of CADASIL in northeast England. Neurology; 78(13): 1025-1027.
View at Publisher | View at Google Scholar - Iafusco D, Massa O, Pasquino B, et al. (2012) Minimal incidence of neonatal/infancy onset diabetes in Italy is 1:90,000 live births. Acta Diabetol; 49(5): 405-408.
View at Publisher | View at Google Scholar - Jakobsson B, Esbjörner E, Hansson S (1999) Minimum incidence and diagnostic rate of first urinary tract infection. Pediatrics; 104(21): 222-226.
View at Publisher | View at Google Scholar - Vogels A, Van Den Ende J, Keymolen K, et al. (2004) Minimum prevalence, birth incidence and cause of death for Prader-Willi syndrome in Flanders. Eur J Hum Genet; 12(3):238-240.
View at Publisher | View at Google Scholar - Jmor F, Emsley HC, Fischer M, Solomon T, Lewthwaite P (2008) The incidence of acute encephalitis syndrome in Western industrialised and tropical countries. Virol J; 5: 134.
View at Publisher | View at Google Scholar - Marras C, Van den Eeden SK, Fross RD, et al. (2007) Minimum incidence of primary cervical dystonia in a multiethnic health care population. Neurology; 69(7): 676-680.
View at Publisher | View at Google Scholar - Hui L, Poulton A, Kluckow E, et al. (2020) A minimum estimate of the prevalence of 22q11 deletion syndrome and other chromosome abnormalities in a combined prenatal and postnatal cohort. Hum Reprod; 35(3): 694-704.
View at Publisher | View at Google Scholar - Wilson D I,. Cross IE, Burn J (1994) Minimum prevalence of chromosome 22q11 deletions. American Journal of Human Genetics; 55(Suppl.3); Conference: 44. annual meeting of the American Society of Human Genetics, Montreal (Canada), 18-22 Oct 1994.
View at Publisher | View at Google Scholar - Madzivire D, Useh D, Mashegede PT, Siziya S (2010) Minimum incidence of congenital talipes equino-varus and post treatment evaluation of residual deformities in a population in Zimbabwe. Cent Afr J Med; 48: 3-4.
View at Publisher | View at Google Scholar - Turabian JL (1995) [Notebooks of Family and Community Medicine. An introduction to the principles of Family Medicine]. Madrid: Díaz de Santos.
View at Publisher | View at Google Scholar - Hart JT (1981) A new kind of doctor. J R Soc Med; 74(12): 871-83.
View at Publisher | View at Google Scholar - Yang J (2024) General practitioners in the UK 2000-2022. Statista; 21.
View at Publisher | View at Google Scholar - Zellweger U, Bopp M, Holzer BM, Djalali S, Kaplan V (2014) Prevalence of chronic medical conditions in Switzerland: exploring estimates validity by comparing complementary data sources. BMC Public Health; 14:1157.
View at Publisher | View at Google Scholar - Schellevis FG, Van de Lisdonk E, Van Der Velden J, Van Eijk JTHM, Van Weel C (1993) Validity of diagnoses of chronic diseases in general practice. The application of diagnostic criteria. J Clin Epidemiol; 46:461-468.
View at Publisher | View at Google Scholar - Barber J, Muller S, Whitehurst T, Hay E (2010) Measuring morbidity: self-report or health care records? Fam Prac; 27 (1): 25-30.
View at Publisher | View at Google Scholar - Esteban-Vasallo MD, Dominguez-Berjon MF, Astray-Mochales J, et al. (2009) Epidemiological usefulness of population-based electronic clinical records in primary care: estimation of the prevalence of chronic diseases. Fam Prac., 26 (6): 445-454.
View at Publisher | View at Google Scholar - Muggah E, Graves E, Bennett C, Manuel DG (2013) Ascertainment of chronic diseases using population health data: a comparison of health administrative data and patient self-report. BMC Public Health; 13: 16.
View at Publisher | View at Google Scholar - Violan C, Foguet-Boreu Q, Hermosilla-Perez E, et al. (2013) Comparison of the information provided by electronic health records data and a population health survey to estimate prevalence of selected health conditions and multimorbidity. BMC Public Health; 13: 251.
View at Publisher | View at Google Scholar - Ashton J (Editor) (1994) Epidemiological imagination. Buckingham: Open University Press.
View at Publisher | View at Google Scholar - Morris JN (2007) Uses of epidemiology. Int. J. Epidemiol; 36 (6): 1165-1172.
View at Publisher | View at Google Scholar - Mackenzie J (2013) A Defence of the Thesis that “The opportunities of the general practitioner are essential for the investigation of disease and the progress of medicine”. Int. J. Epidemiol; 41: 1507-1518.
View at Publisher | View at Google Scholar - Hart JT, Thomas C, Gibbons B, et al. (1991) Twenty-five years of case finding and audit in a socially deprived community. BMJ.; 302:1509-1513.
View at Publisher | View at Google Scholar