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Changes In the Morphology of Neurons of The Parietal Cortex and Hippocampus of Rats in The Dynamics of Step Subtotal Cerebral Ischemia

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Research Article | DOI: https://doi.org/10.31579/2835-8295/010

Changes In the Morphology of Neurons of The Parietal Cortex and Hippocampus of Rats in The Dynamics of Step Subtotal Cerebral Ischemia

  • Bon E.I *
  • Maksimovich N. Ye
  • Zimatkin S.M
  • Holik S.V

Grodno State Medical University, 80, Gorkogo St., 230009, Grodno, Republic of Belarus.

*Corresponding Author: Bon E.I, Grodno State Medical University, 80, Gorkogo St., 230009, Grodno, Republic of Belarus

Citation: Bon E.I Maksimovich N.Ye, Zimatkin S.M., Holik S.V. (2023), Changes In the Morphology of Neurons of The Parietal Cortex and Hippocampus of Rats in The Dynamics of Step Subtotal Cerebral Ischemia, International Journal of Clinical Reports and Studies, 2(1); DOI:10.31579/2835-8295/010

Copyright: © 2023, Bon E.I. This is an open-access artic le distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 25 January 2023 | Accepted: 10 February 2023 | Published: 17 February 2023

Keywords: neurons; parietal cortex; hippocampus; cerebral ischemia

Abstract

The study of the brain in norm and pathology is an urgent and promising direction of modern science and, in this regard, a frequent topic of dissertation research. Cerebral ischemia leads to a number of general and local metabolic and functional disorders, the pathogenesis of which is complex, multifaceted and largely.The aim was to change the morphology of neurons in the parietal cortex and hippocampus of rats in the dynamics of stepwise subtotal cerebral ischemia.With stepwise bilateral ligation of both common carotid arteries with an interval of 7 days, negative changes were least pronounced, especially in the hippocampus. The longer the interval between dressings, the more effectively neurons adapt to lack of oxygen, which makes it possible to further study in more detail the dynamics of the mechanisms of damage development and adaptive changes in the brain.

References

  1. Bon,E.I.(2020)ChangesintheimmunoreactivityofATPsynthaseandchromatophiliaofthecytoplasmofneuronsintheparietalcortexofthebrainofratsunderconditionsofsteppedcerebralischemia/E.I.Bon,N.E.Maksimovich,S.M.Zimatkin//OrenburgMedicalBulletin.-.-No.4.-S.26-23
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